Study on the expression of nuclear factor-?B in ischemia-reperfusion rats
- VernacularTitle:大鼠脑缺血再灌注损伤后NF-?B表达的研究
- Author:
Yu WU
- Publication Type:Journal Article
- Keywords:
Nuclear factor-kappa B;
Ischemia-reperfusion;
Rat
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the role of nuclear factor-?B(NF-?B)in rats with cerebral ischemia-reperfusion injury. Methods:Rat models of cerebral ischemia-reperfusion were established.24hours later,the expression of NF-?B in rat brain of sham-operation group,operation group and intervention group was detected with immunohistochemistry method,Cytokin-induced neutrophil chemotactics(CINC)in rat brain were measured and histopathological examinations were conducted on the hippocampal CAl.Results:The expression of NF-?B p65 and CINC in the operation group increased significantly compared with the sham-operation group(P
