Relationship between vascular endothelial growth factor and interstitial lung involvement in patients with systemic sclerosis
- VernacularTitle:系统性硬化病肺间质病变与血管内皮细胞生长因子的关系
- Author:
Wubin LONG
;
Bin ZHOU
;
Zhongwei ZHOU
;
Jing ZHU
;
Jian LIU
;
Xiaodan WU
- Publication Type:Journal Article
- Keywords:
Scleroderma,systemic;
Lung diseases,interstitial;
Endothelial growth factors
- From:
Chinese Journal of Rheumatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the serum levels of vascular endothelial growth factor (VEGF) and interstitial lung involvement in patients with systemic sclerosis (SSc).Methods We evaluated the serum levels of VEGF by ELISA in patients with active SSc and normal controls,and the correlation between VEGF and the vital capacity diffusion capacity for carbon monoxide of the lung.Results The serum levels of VEGF in patients with SSc (363 ?178) ng/L was significantly higher than that in normal controls (183?59) ng/L (P
