Experimental study of relationship between cerebral vasospasm and clearance rate of red blood cell in cerebral spinal fluid following subarachnoid hemorrhage
- VernacularTitle:脑脊液中红细胞清除速率与脑血管痉挛关系的实验研究
- Author:
Tao XIN
;
Jianmin LIU
;
Bo HONG
- Publication Type:Journal Article
- Keywords:
Subarachnoid hemorrhage;
Cerebral vasospasm;
Red blood cell
- From:Journal of Interventional Radiology
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Investigation of the clearance rate of RBC in cerebral spinal fluid(CSF)after lumber subarachnoid space continuous drainage following subarachnoid hemorrhage(SAH)and the relationship with cerebral vasospasm(CVS) were carried out. Methods An experimental SAH was achieved in dogs by twice injecting fresh autologous arterial blood into cisterna magna of each animal.RBC counts in CSF were measured in the drainage group, puncture group and control group respectively.The degrees of CVS were analyzed through cerebral angiography(%reduction of basilar artery diameter,%RBAD). Results Comparing with puncture group and control group, the drainage group showed a significantly higher clearance rate of RBC with lesser occurrance and degree of CVS. Conclusions RBC and its degeneratives in CSF may be involed in the process of CVS following experimental SAH. Continuous lumber subarachnoid space drainage may prevent CVS.
