Extraction of Volatile Oil from Naokangling Capsule and Processing Techniques of Its p-cyclodextrin Inclusion Compound
- VernacularTitle:脑康灵胶囊中挥发油的提取及?-环糊精包合工艺研究
- Author:
Yan WANG
;
Liling ZHOU
;
Mudan ZHANG
;
Qiwen WANG
- Publication Type:Journal Article
- Keywords:
NAOKANGLING CAPSULE;
VOLATILE OIL;
CYCLODEXTRINS;
ORTHOGONAL DESIGN
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To screen an optimal method for the extraction of volatile oil from Naokangling Capsule (NC) and processing techniques of ?-cyclodextrin (?-CD) inclusion compound of NC. [Methods] The study was carried out with orthogonal design . Oil-extraction ratio, oil-bearing rate and inclusion rate of ?-CD inclusion compound of NC were used as indexes. [Results] The optimal process for oil extraction was adding 10-fold water in medicinal materials and then soaking for one hour and distilling for 5 hours. The optimal processing conditions for ?-CD inclusion compound of NC were: the proportion of ?-CD and volatile oil being 6:1, the inclusion compound being stirred for 2 hours at 40℃ . [Conclusion] This method is simple and practical and can increase the stability of preprations. It can be used for the production of ?-CD inclusion compound in a large scale.