Clinicopathological value of immunohistochemical detection of micrometastases in pT_3N_0M_0 gastric cancer
- VernacularTitle:PT_3N_0M_0胃癌病人淋巴结微转移的临床病理学意义
- Author:
Ziwei WANG
- Publication Type:Journal Article
- Keywords:
Gastric cancer;
Micrometastases;
Cytokeratin;
Immunohistochemistry
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Exploring the significance of micrometastases of lymph nodes in cases of pT 3N 0M 0 gastric cancer.Methods:We examined 2230 lymph nodes that had been removed from 95 patients with stage Ⅱ gastric cancer(pT 3N 0M 0) with immunostaining of cytokeratin.Results:In 38 of 95(40%) patients with gastric cancer,evidence of micrometastases was found in 290 of 2230(13%) lymph nodes.The incidence of micrometastases in undifferentiated carcinoma was higher than that in differentiated carcinoma.An analysis of survival demonstrated the 5-year survival of patients with micrometastases in their resected lymph nodes was significantly lower than that of patients without micrometastases( P
