The changes in blood glucose and insulin after traumatic brain injury in rats
- VernacularTitle:大鼠创伤性脑损伤后血糖与血清胰岛素变化规律的研究
- Author:
Zhaohui HE
- Publication Type:Journal Article
- Keywords:
Traumatic brain injury;
Blood glucose;
Insulin
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study changes in blood glucose and insulin in rats after traumatic brain injury.Methods:Based upon the Feeney's model, the blood glucose and insulin concentration of each animal group were measured 1/2 hour before the injury and 6?12?24?48?72?120 hours after the injury.Results:The blood glucose concentration increased markedly in each injured group after the injury.The severer the trauma was, the faster the blood glucose increased and the higher the concentration peak reached.The blood insulin concentration increased markedly in moderately and severely injured group,but not in lightly injured one.The severer the trauma was, the faster the blood insulin increased and the higher the concentration peak reached.Conclusion:The post-traumatic hyperglycemia is probably associated with insulin resistance or the changes of the hormones which can raise or drop the insulin level.