The clinical observation of the treatment of the moderate and severe amblyopia with cytidine-5' -diphosphocholine
- VernacularTitle:胞二磷胆碱治疗中、重度弱视的临床观察
- Author:
Li ZHANG
- Publication Type:Journal Article
- Keywords:
Cytidine-5-diphosphocholine;
Amblyopia;
Medical therapy
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the change of quotas such as vision acuity,fusion acuity etc after CDP-choline therapy,and evaluate comprehensively the curative effect and feasibility of it.Methods:Eighty-one amblyopic subjects were divided into 3 groups randomly:medical group with CDP-choline administration,combined group CDP-choline administration plus occlusion and meticulous work,occlusion group occlusion and meticulous work.Various kinds of side effects were carefully observed and all results were analyased statistically.Results:The appearance of the improvement of visual acuity in medical group was the earilest,but deteriorated gradually after 4 months.The combined group had improvements in all kinds of amblyopia,lasting throughout the observation period.Retina light sensitivity significantly increased in the medical group and combined group.The latency of the P 100 wave was not improved after the treatment in all of the three groups.Moreover,generalized tonic-clonic seizure was induced by CDP-choline administration in one subject.Conclusion:CDP-choline can improve the VA of amblyopic eyes,and raise the retina light sensitivity.CDP-choline treatment plus occlusion has a better curative effect.CDP-choline may induce seizure.
