Study on preparing Danshen Injection by micelle-ultrafiltration
- VernacularTitle:胶团超滤法制备丹参注射液
- Author:
Dan WANG
;
Tao GONG
;
Bing SUN
;
Li LI
;
Fangmi FU
- Publication Type:Journal Article
- Keywords:
Danshen Injection;
micelle-ultrafiltration;
Tween-80;
protocatechualdehyde
- From:
Chinese Traditional Patent Medicine
1992;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To prepare Danshen Injection (Radix Salviae Miltiorrhizae) by micelle-ultrafiltration. Methods: For preparing Danshen Injection, we packed the impurities in the macrofiltered liquor of Radix Salviae Miltiorrhizae with micelle of Tween-80, and ultrafiltered the compounds with ultrafiltration membrane withholding molecular weight more than 50000. Then we evaluated the process with the comprehensive indexes including loss rate of UV absorbance, loss rate of Protocatechualdehyde and the stability of transparence. Conclusion: The process of Danshen Injection prepared by micelle-ultrafiltration is better than that of ordinary ultrafiltration.
