Effects of Bushendingchuan Decoction on the blood level of CORT and expression of hypothalamic CRHmRNA in asthmatic rats
- VernacularTitle:补肾定喘汤对哮喘大鼠血CORT、下丘脑CRHmRNA表达的影响
- Author:
Changchun MAO
;
Zhaoqin FANG
;
Dunxu WU
;
Jianhua XU
;
Dongyua GUAN
- Publication Type:Journal Article
- Keywords:
Bushendingchuan Decoction;
corticotropin-releasing hormone;
mRNA;
corticosterone
- From:
Chinese Traditional Patent Medicine
1992;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the change of the blood level of CORT and expression of CRHmRNA in asthma-tic rats and the effects of Bushendingchuan Decoction(Cornu Cervi, Herba Cistanches, Radix Morindae Officinalis, Radix Rehmanniae Preparata, etc.) on them. Methods: The change of level in CORT was measured by radioimmunoassay, the change of level in hypothalamic CRHmRNA was measured by RT-PCR(Reverse transcription and polymerase chain reaction by the semi-quantitative determination). Results: The blood level of CORT decreased(P
