Study on extraction technology of Zhixuan Granula
- VernacularTitle:止眩颗粒剂的提取工艺研究
- Author:
Hongmei WEN
;
Wei LI
;
Guoping PENG
;
Quan ZHU
;
Zhengxin ZHANG
- Publication Type:Journal Article
- Keywords:
Zhixuan Granula (ZXG);
orthogonal test;
23-acetate alisol B;
atractylenolide I;
sedation
- From:
Chinese Traditional and Herbal Drugs
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To optimize the preparation procedure for Zhixuan Granula (ZXG). Methods The optimum extracting conditions of ZXG were selected by orthogonal test with the active components: 23-acetate alisol B, atractylenolide I, and dried extract as the index, it mice sedation of ZXG was clarified by pharmacodynamics. Results The optimum preparation procedure was as follows: Rhizoma Alismatis and Rhizoma Atractylodis Macrocephalae were extracted with alcohol first, adding 12-fold 70% alcohol by refluxing, extracting twice, 2 h once, then extracted with water, adding 14-fold water, extracting twice, 2 h once. The extract showed the obvious effect on sedation of mice. Conclusion The optimum preparation procedure is reliable, with higher extracting ratio of the active components.
