Study of relationship between some autoantibodies and chronic liver disease
- VernacularTitle:慢性肝病与?_2糖蛋白Ⅰ抗体及其他自身抗体的关系
- Author:
Pujun GAO
;
Yunfeng PIAO
;
Like QU
- Publication Type:Journal Article
- Keywords:
Chronic liver disease;
?2-glycoprotein Ⅰ;
Autoantibody
- From:
Chinese Journal of Digestion
1996;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between some autoantibodies including anti-? 2-glycoprotein Ⅰ (anti-? 2GPⅠ) and chronic liver disease. Methods A cohort of patients with chronic hepatitis B (CHB) and post-hepatitis B cirrhosis (PHBC) was studied for the serum anti-? 2GPⅠ levels by ELISA with purified ? 2GPⅠ as antigen. The serum dsDNA, smooth muscle antibody (SMA) and ribonucleoprotein antibody (RNPA) were also detected. Results High positive rate was observed in patients with CHB or PHBC (20.9%, 9/43; 49.3%,35/75) comparing with that in control group (3.1%, 1/32) ( P
