Study on HPLC fingerprint quality control model for traditional Chinese medicine
- VernacularTitle:HPLC指纹图谱的中成药质量控制模式研究
- Author:
Lingji ZENG
;
Mao CHEN
;
Deqing WANG
;
Dongsheng YANG
- Publication Type:Journal Article
- Keywords:
HPLC;
fingerprint;
quality control model
- From:
Chinese Traditional Patent Medicine
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study an identifying model of HPLC fingerprint for the overall quality control of traditional Chinese medicine. Methods: A HPLC method is used to establish the standard fingerprint as well as sample fingerprint first. Then through the principles of numerical taxonomy and statistics, the similarity of the sample to the standard is tested by coefficients of cosine and distant, which are calculated with computer. Results: The combination of the two coefficients of cosine and distant can test the similarity of the sample to the standard correctly and accurately. Conclusion: The coefficients along with HPLC fingerprint can be applied to the on-line control in workshop to ensure the products' quality of all batches.
