Experiment on pharmadynamics and acute toxicity of Sanyuzhitong Pills
- VernacularTitle:散瘀止痛接骨丸药效学及急性毒性实验
- Author:
Xinchun WANG
;
Xinling ZHU
;
Xinming ZHOU
;
Xin LI
- Publication Type:Journal Article
- Keywords:
Sanyuzhitongjiegu Pills, pharmadynamics, acute toxicity
- From:
Chinese Traditional Patent Medicine
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the pharmadynanics and acute-toxicity of Sanyuzhitongjiegu Pills Methods: Hot plate, body-twisted, in flammation caused by dimethyl benzene, cotton ball method, fracture-healed hare and hemorrheology were applied. Results: Sanyuzhitongjiegu Pills could markedly reduce the twisting times of mice and prolong the initiate of pain caused by heat irritation, inhibit mice's ear swelling caused by dimethyl benzene, diminish the weight of rat's myoidem, promote the healing of experimental fracture, reduce the sticky property of whole blood and improve hemorrheology. The maximum of dosage for mice is 10g?kg -1 , all of them survived for 7 day. Conclusion: Shayuzhitong Pills have effect on pain-killing, anti-inflammation, promotion of fracture healing, regulation of blood, remove of stagnant, The Pills have little toxicity.
