Experimental study of electrochemotherapy on implanted liver tumor cells apoptosis of rats
- VernacularTitle:电化学治疗诱发大鼠种植型肝癌细胞凋亡的实验研究
- Author:
Chengwei SHAO
;
Peijun WANG
;
Jianming TIAN
- Publication Type:Journal Article
- Keywords:
Neoplasm, liver;
Electrochemotherapy;
Apoptosis;
Animal model
- From:
Journal of Interventional Radiology
1994;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effects of electrochemotherapy (EChT) on implanted liver tumor cells apoptosis of rats.Methods Immediate cancerous ascitis injection method was used for the formation of rats liver tumor model and then followed by rats liver tumor treatment with EChT. Tumor size, necrosis and apoptosis indexes were observed after one week by imaging or pathologic method. The results were compared with those of control group. Results Before EChT, rats liver tumor volume appeared as (100?6)mm 3 and turned to be (125?10)mm 3 one week after EChT, which were significantly smaller than those of the control group [(190?11)mm 3], P
