Experimental Study on Effect of Huangqi Danshen Drop Pill on Pituitary - Induced Acute Myocardium Ischemia
- VernacularTitle:黄芪丹参滴丸抗垂体后叶素致大鼠急性心肌缺血的实验研究
- Author:
Yi WANG
;
Xiumei GAO
;
Boli ZHANG
- Publication Type:Journal Article
- Keywords:
@ Huangqi Danshen Drop Pill/pharmacology;
@Myocardium ischemia/TCD therapy;
Disease model, animal;
Pituitary
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Huangqi Danshen Drop Pill(HDDP) on pituitary (Pit) induced acute myocardium ischemia. Methods Acute myocardium ischemia rat model was established by sublingual venous injection of Pit(0. 35U/kg). The changes of the T wave ( II channel ECG) and serum contents of lactate dehydrogenase (LDH), CK, superoxide dismutase (SOD) and malondialdehyde (MDA) were observed in various times after Pit injection. Results HDDP could significantly lower the height of T waves, increase SOD activity and decrease MDA content. Conclusion HDDP can improve acute myocardium ischemia induced by Pit.
