Protective Effect of Yugan Tablet on D - galactosamine - induced Acute Hepatic Injury in Mice
- VernacularTitle:愈肝片对D-氨基半乳糖小鼠急性肝损伤的保护作用
- Author:
Lichang LIU
;
Lei ZHANG
;
Yifeng DENG
;
Ming ZHOU
;
Yonghe ZHANG
- Publication Type:Journal Article
- Keywords:
YUGAN TABLET/phannacology;
HEPATIC INJURY/TCD therapy;
ASPARTATE AMINOTRANSFERASE /blood;
ALBUMINS/blood;
DISEASE MODELS, ANIMAL;
MICE
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To observe the protective effect of Yugan Tablet (YT) on D-galactosamme-induced acute hepatic injury in mice. [ Methods ] Mice were randomly allocated to normal control group, model group, Ganpi Kang Capsule group and YT groups (low-, moderate- and high-dosage YT). Serum levels of aspartate transaminase (AST) and albumin (ALB) and clotting time (CT) were examined to evaluate the effects of YT and Ganpi Kang Capsule on mice with D-galactosamine-induced acute hepatic injury. [Results] Serum level of AST was increased ( P