Study on extracting purified active components of Picria fel-terrae, Scutellaria baicalensis and Phellodendron chinense with macroporous resins
- VernacularTitle:苦玄参、黄芩与黄柏的大孔树脂提取研究
- Author:
Jieming ZOU
;
Hao LU
;
Bin HE
;
Minju WU
- Publication Type:Journal Article
- Keywords:
Picria fel-terrae Lour.;
picfelterraenin Ⅰ A;
Scutellaria baicalensis Georgi;
baicalin;
Phellodendron chinense Schneid;
berberine hydrochloride;
macroporous resin
- From:
Chinese Traditional and Herbal Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To study the application of macroporous resins to the purified active components of Picria fel-terrae Lour., Scutellaria baicalensis Georgi, and Phellodendron chinense Schneid. Methods With the purified active components of Chinese materia medica (CMM) as a standard, we selected the suitable macroporous resins and studied the optimum technological parameters of the adsorption and elution. Results The suitable three types of macroporous resins which were used to the purified active components of CMM were HPD500 for P. fel-terrae., HPD300 for S. baicalensis, and HPD100 for P. chinense. In the absorption course, when the ratios between the medicinal materials amount and the volume of macroporous resins were 1.5 for P. fel-terrae, 0.5 for S. baicalensis and 1 for P. chinense, the purified active components of CMM appeared leaking, and were no more absorbed when the ratios were 11 for P. fel-terrae, 2 for S. baicalensis and 4.75 for P. chinense. In the elution course, the optimum alcohol concentrations were 50% for P. fel-terrae, 30% for S. baicalensis and 50% for P. chinense. Conclusion It is obviously different to refine the active components of CMM, while using the diverse types of macroporous resins.
