Activation and significance of NF -kBp65 on the lesion of glomerulus in active Heymann nephritis
- VernacularTitle:NF-?Bp65在主动性Heymann肾炎肾小球损伤中的作用
- Author:
Xiaogang DU
- Publication Type:Journal Article
- Keywords:
Active Heymann nephritis;
Glomerulus;
Nuclear factor-?B
- From:
Journal of Chongqing Medical University
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the activation and significance of NF- ?Bp65 in active Heymann nephritis in rats. Methods : Female Wistar rats 6~8 weeks of age were used. The nephritis was induced with FxIA/CFA by subcutaneous injection and the control group with CFA . After the rats were killed, the activation of NF- ?Bp65 in renal tissue was observed by use of immunohistochemical dyeing ;also observed were the changes in pathology ,urinary protein and albumin and the relationship between these 3 factors. Results: Compared with the control group, the thickness of GBM increased (F
