Experimental Study on Niaoduqing Ta blet in Treating Chronic Renal Failu re
- VernacularTitle:尿毒清片治疗慢性肾功能衰竭的实验研究
- Author:
Hongzhu DENG
;
Wei XIAO
- Publication Type:Journal Article
- Keywords:
Niaoduqing Tablet /pharmacology;
Renal failure,chronic /TCD therapy;
Renal failure,chronic /phys-iopathol;
Renalfailure,chronic /pathology;
Disease models,animal
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effects of Niaoduqing Tablet and Niaoduqing Granule in tre atingchronic renal failure(CRF)induced by adenine in rats,which is expected to provide some lab oratory data for the clinical applic ation and innovation of the dosage forms.Methods CRF rat models induced by adenine were administered with Niaoduqing Tabl et or Niaoduqing Granule and then the seru m levels of BUN and Scr,haematologic al and biochemical indexes and renal histolog-ical features were observed.Results Both of two forms reduced serum levels of BUN and Scr,ameliorate the electrolyte,increase the number of red blood cell,hemoglobin content and haematocrit and alleviate pathological changes of the kidney tissue.Conclusion Both Niaoduqing Tablet and Niaoduqi ng Granule is effective in treating CRF in rats and the effect of Niaoduqing Tablet in ameliorating a nemia is superior to that of Niaoduqi ng Granule.
