Experimental Study of Gout Granule f or Gout
- VernacularTitle:痛风冲剂抗痛风作用的实验研究
- Author:
Lian NING
;
Ruomin JIN
;
Yaoping WU
;
Haigui ZHANG
;
Haihong QI
;
Ming ZHANG
;
Bi LI
- Publication Type:Journal Article
- Keywords:
Gout Granule /pharmacology;
Gout /TCD therapy;
Disease models,animal
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Gout Gra nule(GG)for gout.Methods Gout -relieving effect of GG was observed in rats with adjuvant arthritis induced by sodium urate and i n mice with hyperuricemia induced by hypoxan-thine.Anti -inflammation of GG was i nvestigated in mice with xylene -ind uced auricular swelling and in rats with edema of hind paw induced by injection of carrageenin.WBC migratory response c aused by carboxymethylcellulose(CMC)in mice was also observed.Results GG could reduce the blood level of uric acid and inhibit acute inflammatio n in model ani-mals and also tended to promote the elimination of uric acid.Conclusion GG had a remarkable effect on the acut e attack of gout.
