Two cases of acute renal failure complicated by the poisoning of amanita virosa.
- Author:
Hyun Chul JUNG
1
;
Bo Suk KIM
;
Sang Heun SONG
;
Yong Bum KIM
;
Ho Jin SIN
;
Dong Won LEE
;
Woo Chul LEE
;
Soo Bong LEE
;
Ihm Soo KWAK
;
Ha Yeon RHA
Author Information
1. Department of Internal Medicine, College of Medicine Pusan National University, Pusan, Korea.
- Publication Type:Case Report
- Keywords:
Renal failure;
Amanita virosa;
Mushroom
- MeSH:
Acute Kidney Injury*;
Agaricales;
Amanita*;
Atrophy;
Biopsy;
Blood Urea Nitrogen;
Creatinine;
Gastroenteritis;
Hepatocytes;
Inflammation;
Kidney;
Microscopy;
Mushroom Poisoning;
Necrosis;
Pancreas;
Poisoning*;
Renal Insufficiency
- From:Korean Journal of Medicine
1999;57(6):1053-1060
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Although the most of mushroom poisoning have a clinical menifestation of mild to moderate gastroenteritis, some mushroom may cause a serious illness; acute renal failure, hepatic necrosis. We experienced two cases of acute renal failure complicated by the poisoning of amanita virosa. Amanita virosa have a amatoxin. Amatoxin deteriorate hepatocytes, renal tubular cells, intestinal mucosal cells, and pancreas. They were transferred from local hospital for renal failure management. On admission, blood urea nitrogen and serum creatinine were highly elevated. We diagnosed acute renal failure complicated by poisoning of amanita virosa. In one case, renal function was further deteriorated compared with initial laboratory findings after creatinine was normalized at fifth day. Thus, we did a kidney biopsy. Light microscopy and EM showed interstitial inflammation and moderate tubular atrophy. They were recovered with the supportive management. We report two cases of mushroom poisoning-induced acute renal failure with review of literature.
