Basic and clinic study of the density proportion in forming AVM embolic agent-NBCA mixed liquid.
- VernacularTitle:CAVM栓塞剂NBCA混悬液配比浓度的基础和临床研究
- Author:
Wenbin LU
;
Yizhi LIU
;
Yonghai JIN
- Publication Type:Journal Article
- Keywords:
N butyl cyanoacrylate;
Cerebral arteriovenous malformations;
Embolization;
Arteriovenous circulation time
- From:
Journal of Interventional Radiology
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective By analysing the relation between the proportion of NBCA and the arteriovenous circulation time will give the optimal proportion of NBCA for embolizing cerebral AVM with microcatheter clinically.Methods (1) The fresh aterial blood fractions from intracranial hemorrhage in vitro of 16 cases were mixed with the 20%、33%、50%、70% and 80% NBCA respectively and evaluated the coagulation times with the different densities of NBCA in the fresh aterial blood in vitro; (2) two cases were performed with superselective embolotherapy to five feeding arteri. Results (1) the correlation index between different densities of NBCA and the fresh areterial blood in vitro , T (c) =e 1.9994-1.487D , (2) about 90% nidus of AVM were occluded after embolization, and the fistulas of AVF were basically closed after embolization.Conclusions There is a mathematical model between the arteriovenous circulation time and the proportion of NBCA, thus providing the theoretical clinical application of the embolotherapy of CAVM with microcatheter.
