Effects of Electroacupuncture on Learning and Cerebral Heme Oxygenase Activity in Rats with Vascular Dementia
- VernacularTitle:电针对血管性痴呆模型大鼠学习记忆行为及脑血红素氧化酶活性的影响
- Author:
Li WANG
- Publication Type:Journal Article
- Keywords:
DEMENTIA, VASCULAR /acup - mox therapy;
LEARNING/acup - mox effects;
MEMORY / acup - mox effects;
POINT GV20 (BAIHUI);
POINT GV14 (DAZHUI);
HEME OXYGENASE/ acup - mox effects;
HIPPOCAMPUS
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To observe the effect of electroacupuncture (EA) on learning and cerebral heme oxygenase (HO) activity in rats with vascular dementia (VD). [Methods] Sixty rats were randomly allocated to mimic group (Group A), EA group (Group B), nimotone group (Group C) and model group (Group D) . Rat models of VD were established by 4 - vessel occulusion (4 - VO) method. Ten days after modeling, Group B was trested with EA on Baihui (GV20) and Dazhui (GV14), one time per day; Group C with nimotone, 20ml/kg body weight, ig, qd. The treatment course lasted 15 days. And then the learning was estimated with Morris water maze and HO activity in cortex and hippocampus (HC) of rats was also measured. [Results] Mean escape latency within 6 days in EA group was shorter than that in model group ( P 0.05). In EA group, the swimming times in the original platform quadrant were more than that in the right, left or opposite quadrant and also more than that in the original platform quadrant in the model group (P
