Study on fingerprints of Radix Salviae Miltiorrhiza and its INJECTION by HPLC-MS
- VernacularTitle:丹参及丹参注射液指纹图谱的HPLC-MS研究
- Author:
Zunjian ZHANG
;
Qian LI
;
Wei WANG
;
Qiaogen ZOU
;
Luhua ZHAO
- Publication Type:Journal Article
- Keywords:
Radix Salviae Miltiorrhizae (RSM);
RSM INJECTION;
fingerprint;
HPLC-UV;
HPLC-MS
- From:
Chinese Traditional and Herbal Drugs
1994;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To investigate the chromatographic fingerprints of Radix Salviae Miltiorrhizae (RSM), its intermediate and INJECTION by HPLC-UV-MS. Methods Separation was performed on an Alltima C 18 analytical column with the mobile phase consisting of methanol-water-acetic acid as gradient eluent at the flow rate of 1 mL/min. The UV detection was set at 281 nm and TIC was recorded by an electrospray ionization mass spectrometer in negative ion mode. Results The HPLC-UV and HPLC-MS fingerprints of RSM, its intermediate and INJECTION were obtained with perfect isolation. Conclusion The fingerprints could be used for the control of RSM, its intermediate and INJECTION.
