Changes of bone density and bone metabolic markers in patients with lupus nephritis after prednisone treatment
- VernacularTitle:狼疮肾炎泼尼松治疗后骨密度及骨代谢指标的变化
- Author:
Wen LU
;
Li HAO
;
Qiu ZHANG
;
Yibo SHAO
;
Minggong YANG
- Publication Type:Journal Article
- Keywords:
Lupus nephritis;
Prednisone;
Bone density
- From:
Chinese Journal of Rheumatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes of the bone density and metabolic makers in patients with lupus nephritis (LN) after long time prednisone treatment.Methods All patients were women.The healthy controls (group A, n =20),the patients with normal renal function (group B, n =25) were studied before and after 2 and 4 month prednisone treatment.Dual energy X ray absorptiometry was used to measure bone mineral density (BMD) in the lumbar spine at L2～L4,femoral neck,Ward′s triangle,great trochanter (GT) and ultradis (ULT).Simultaneously,the serum calcium,phosphate,alkaline phosphate enzyme,PTH M,BGP,24 hour urine calcium,creatinine and other biochemical indices were examined in all of them.Results ① There were no significant differences in BMD between both groups ( P
