Biological function of IL-23
10.3969/j.issn.1000-3606.2010.03.027
- VernacularTitle:白介素-23的生物学功能
- Author:
Yanchun LI
;
Jirong LU
- Publication Type:Journal Article
- Keywords:
IL-23;
biological function;
diseases
- From:
Journal of Clinical Pediatrics
2010;(3):295-296,299
- CountryChina
- Language:Chinese
-
Abstract:
Interleukin(IL),generated by immunocytes or non-immune cells,is a group of cell factors that holds many important biological effects. Up to now,with the rapid progress of molecular biology and cell biology technique,29 types(IL-1 ～ IL-29)of IL have been reported since its denomination in 1979. IL-23,one kind of interleukin found in 2000,is composed of p19 and p40 sub group. Recent studies showed that it has various biological functions,such as acting on T cell to make it produce various cell factors,acting on DC and MP to affect the secretion of the relevance cell factors. The biological functions of IL-23 have played an important role in various diseases. This review describes the molecular structure,biological function,and its effects on related diseases.
