Antitumor Effects of Polysaccharide from Spirulina Platensis
- VernacularTitle:螺旋藻多糖抗肿瘤作用研究
- Author:
Hongquan ZHANG
;
Hongping YIN
;
Min WANG
;
Yun SUN
;
Xiaomei LIU
- Publication Type:Journal Article
- Keywords:
Polysaccharide from spirulina platensis /pharmacology;
Neoplasms/TCD therapy;
Disease models , animal
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the antitumor effect of polysaccharide from spirulina platensis(PSP), and its synergic and attenuated effects on chemotherapeutic drugs in tumor-bearing mice. Methods: Mouse models of transplanting tumor were established. Antitumor effects of PSP and PSP combined with chemotherapeutic drugs were observed and the effect of PSP on leukopenia induced by chemotherapeutic drugs was also investigated. Results: PSP significantly inhibited S180 and H22, the inhibitory rate being 50 %-58 %and 43 %-51 %respectively. PSP evidently increased the antitumor action of cytoxan, PDD and 5-Fu, and elevated the number of white blood cells in leukopenia. Conclusion: PSP can obviously inhibit the tumor growth, also has synergic and attenuated effects on chemotherapeutic drugs.
