Effects of Angong Niuhuang Wan on Amounts of Isoenzymes of Serum Lactate Dehydrogenase in Rats with Cerebral Infarct
- VernacularTitle:安宫牛黄丸对脑梗塞造型大鼠血清乳酸脱氢酶同工酶的影响
- Author:
Yishan TANG
;
Huaxin PAN
;
Peixun WANG
;
Ningsheng WANG
- Publication Type:Journal Article
- Keywords:
Angong Niuhuang Wan/drug effects;
Lactate dehydrogenase isoenzymes/blood;
Cerebral;
Disease models , animal
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the different effects of Angong Niuhuang Wan on normal and pathological body. Methods:Cerebral infarct rat models were established by photochemically initiated thrombosis. The rats were randomly allocated to four groups. The control group and the model group were treated with 0.9%NaCl for seven days, and the control+drug group and the model+drug group with Angong Niuhuang Wan 0.13g/kg for seven days. Then amounts of idoenzymes of serum lactate dehydrogenase(LDH1～5) were determinated by the method of gel electrophoresis. Results:The amounts of LDH1 and LDH2 in the model group increase obviously as compared with the control group(P
