A new gene in systemic lupus erythematosus pathogenesis
- VernacularTitle:系统性红斑狼疮与TFAR19的相关性的研究
- Author:
Qinghua SONG
;
Chunhui DI
;
Yingcheng ZHONG
;
Xuerong CHEN
;
Shiyin LI
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus,systemic;
Apoptosis;
Genes
- From:
Chinese Journal of Rheumatology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the role of a new apoptosis related gene TFAR 19 in the pathogenesis of systemic lupus erythematosus (SLE) and the relationship between TFAR 19 and SLE.Methods ELISA was used to test if there is relation between TFAR 19 and SLE.Results It was found that in active SLE patients there was higher titer of TFAR 19 antibody than that in stability patients and normal controls.No significant difference was seen between stability patients and normal controls.Conclusion It is first put forward that TFAR 19 may be related with SLE pathogenesis and disease activity.
