Study of the correlation between time window and effects of urokinase thrombolytic therapy in treating STEMI
10.3969/J.ISSN.1672-8270.2014.06.033
- VernacularTitle:尿激酶溶栓治疗ST段抬高型心肌梗死的时间窗与疗效的相关性研究
- Author:
Surong ZHANG
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
ST segment elevation;
Urokinase;
Thrombolytic therapy
- From:
China Medical Equipment
2014;(6):96-98,99
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the correlation between time window and effects of urokinase thrombolytic therapy in treating STEMI. Methods: STEMI patients in our hospital were enrolled and randomly divided observation group received thrombolytic therapy within 3 h after infarction and control group received thrombolytic therapy 3-6 h after infarction. Then myocardial cells necrosis index and ventricular diastolic function indexes were detected. Results: (1)cTnT, LDH,CK-MB levels of observation group were lower than those of control group and positively correlated with thrombolysis time; (2)E peak, E/A value, LVEF, LVEDD of observation group were higher than those of control group and negatively correlated with of thrombolysis time. Conclusion:short thrombolysis time has positive clinical value in treating STEMI for the myocardial necrosis is less and ventricular function recovery is better.
