STUDY OF TRANSPLANTATION OF SPINAL NEURAL STEM CELLS INTO MICE RETINA
- VernacularTitle:脊髓神经干细胞对小鼠视网膜移植的研究
- Author:
Jinhong MENG
;
Na LUO
;
Gong JU
- Publication Type:Journal Article
- Keywords:
Neural stem cells;
Retina;
Transplantation;
Mice
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the integration and differentiation of spinal neural stem cells after transplantation into mice retina. Methods Primary cultured neural stem cells were transplanted into mice retinas,then the integration ratio and the differentiation pattern of the donor cells were estimated with immunohistochemistry method. Results 1.The integration ratio decreased with the age of the host mice.2.The grafts differentiate into both glia and neuronal cells after transplantation.Conclusion The integration and differentiation of the primary cultured spinal NSC were modulated by both endogenous and exdogenous factors,which provided new proofs for the study of the in vivo differentiation of the NSC.
