A STUDY ON NGF EXPRESSION IN LOWER RESPIRATORY TRACT AND VISCERAL AFFERENT SYSTEM OF ASTHMATIC GUINEA PIG
- VernacularTitle:哮喘豚鼠下呼吸道及内脏传入部位NGF表达的研究
- Author:
Dongpei LI
;
Liping CAI
;
Xiubi FANG
- Publication Type:Journal Article
- Keywords:
Nerve growth factor;
Airway epithelia;
Spinal ganglia;
Spinal dorsal horn;
Asthma;
Guinea pig
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of nerve growth factor(NGF) in the lower respiratory tract and the visceral afferent system of asthmatic guinea pigs. Methods By means of immunohistochemistry and in situ hybridization combined with the micro-image analysis to investigate the alterations of NGF immunoreactivity and mRNA expression in asthmatic guinea pig. Results The positive NGF immunoreactivity was increased in airway epithelia,C-7-T-5 spinal ganglia and correspondent spinal dorsal horn in the asthmatic guinea pigs compared with the controls(P
