Building of transplanted model of Vx-2 carcinoma in rabbit liver and its DSA features
- VernacularTitle:兔Vx-2移植性肝癌模型的建立及其影像学表现
- Author:
Hongxin ZHANG
;
Zhimin WANG
;
Wei CAO
- Publication Type:Journal Article
- Keywords:
Rabbit;
Vx 2;
Liver tumor;
DSA
- From:
Journal of Interventional Radiology
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a stable transplanted model of Vx 2 carcinoma in rabbit from three different transplanted methods, and analyze the DSA (digital substraction angiography) features of the implanted tumors. Methods 60 white rabbits of New Zealand were divided into 3 groups at random, 20 for each group. In the first group, Vx 2 carcinoma cells (about 5?10 7 )were infused via hepatic artery into the rabbit liver. For the second group, Vx 2 carcinoma cells (about 5?10 7 ) were inplanted into the left lobe of the liver via laparotomic route and in the 3rd group with the same route as the 2nd group, a piece of tumor tissue (contained about 10 6 10 8 carcinoma cells) were implanted into the left lobe of the liver. And then a comparative observation was performed in 3 groups included:1. the successful rate of implanted tumors; 2. the volume change and the growth rate of implanted tumors; 3. the biological features of implanted tumors in histopathology and electronic microscope photographs and DSA features of implanted tumors. Results The successful rates of transplanted tumors in the three groups were 7/20, 10/20 and 19/20 respectively. The successful rate of the 3rd group was the highest of the 3( P
