Effect of Buxin Huoluo Capsule for Coronary Heart Disease and Its Anti-lipid-peroxidation Mechanism
- VernacularTitle:补心活络胶囊对冠心病及其脂质过氧化作用的影响
- Author:
Zehong ZHAO
;
Zuyun ZHENG
;
Lingxiang FAN
;
Mingxiang HAN
;
Jingyuan LI
;
Weidong OUYANG
;
Song XUE
;
Shu XU
- Publication Type:Journal Article
- Keywords:
BUXIN HUOLUO CAPSULE/phannacology;
CORONARY DISEASE/TCD therapy;
LIPID PEROXIDES/analysis;
SUPEROXIDE DISMUTASE/analysis
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To evaluate the therapeutic effect of Buxin Huoluo Capsule (BHC) for coronary heart disease (CHD) and to explore its anti-lipid-peroxidation mechanism. [Methods] One hundred and seventy-five cases of CHD were treated with BHC and 121 cases with isosorbide dinitrate (ID) . Effects of BHC on angina pectoris, electrocardiograph, superoxide dismutase (SOD) activity and lipid peroxides (LPO) level were observed. [Results] In BHC group, the total effective rate in relieving angina pectoris was 88.0 % and that in improving electrocardiogram was 80.0 % , the difference being not significant as compared with ID group. As for the reduction of frequency of angina pectoris and the decrease of dosage of nitroglycerin, BHC were superior to ID. Furthermore, BHC decreased LPO level and increased SOD activity, the difference being significant (P
