Protective Effect of Xing Nao Jing on Cultured Cortical Neurons in Rats
- VernacularTitle:醒脑静对大鼠皮层神经细胞的保护作用
- Author:
Wencheng WAN
;
Jiefen LI
;
Haiyan WO
;
Xiaoying LI
;
Shaoqiong ZHANG
- Publication Type:Journal Article
- Keywords:
XING NAO JING/phamiacology;
NEURONS/drug effects;
MOSCHUS/pharmacology;
BORNEOLUM SYNTHETICUM /pharmacology
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To study the protective effect of Xing Nao Jing (XNJ) on cultured cortical neurons in rats. [Methods] Primary cultured cortical neurons were applied to observe the effect of XNJ in counteracting the excitotoxicity ofglutamic acid. [Results] XNJ decreased the release of intracellular lactic dehydrogenase induced by glutamic acid and reduced the histological changes of cultured cortical neurons. [Conclusion] XNJ can counteract the excitotoxicity of glutamic acid and protect cultured cortical neurons in rats.
