Effects of Shenxiong Xintong Pill on Cardiac Hemodynamics
- VernacularTitle:参熊心痛丸对心脏血流动力学作用的实验研究
- Author:
Yuanpeng ZHOU
;
Yi YAN
;
Xinjie PENG
;
Wei XU
- Publication Type:Journal Article
- Keywords:
Shenxiong Xintong Pill/pharmacology;
@Coronary blood flow/drug effects;
Coronary resistance/drug effect
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effect of Shenxiong Xintong Pill(SXP) on cardiac hemodynamics. Methods: Parameters of cardiac hemodynamics were examined in anesthetic chest-opened dogs medicated with various doses of SXP. Results: After intraduodenal administration of SXP of 2.0g/kg, the coronary blood flow was raised, coronary resistance decreased, heart rate slowed and the left ventricular diastolic end pressure fallen in the dogs. No obvious changes were found in the contraction , works and ejection of left ventricle. Conclusion: The mechanism of SXP in relieving angina pectoris was probably related to the dilatation of coronary artery and increase of coronary flow with the increase supply of oxygen.
