Studies on the Pharmacodynamics of Niao Gan Ning
- VernacularTitle:尿感宁的主要药效学研究
- Author:
Qi CHEN
;
Qiangmin XIE
;
Yangmei DENG
;
Yu SHI
;
Lan YU
;
Xiaom LIU
;
Yun SUN
- Publication Type:Journal Article
- Keywords:
Niao Gan Ning/pharmacology;
Urethritis/TCD therapy
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the anti-inflammatory, bacteriostatic, diuretic, antispasmodic and immunoenhancement effect of Niao Gan Ning(NGN). Methods: The tests of inhibiting the leukocyte infiltration, in-vitro bacteriostasis, water loading with metabolism cage, isometric tension recording and the phagocytosis of abdominal macrophages(AM) were conducted. Results: NGN could obviously inhibit the wandering of leukocyte in abdominal cavity and decreased the number of WBC in mice, and exert bacteriostatic effect to various degrees. NGN also increase the urine volume in water load rats, inhibited contraction of bladder and ureter smooth muscle induced by Carbacol and histamine in rabbits and rats, and increased phagocytosis of the chicken red cells by AM. Conclusion: NGN has a strong anti-inflammatory, bacteriostatic, diuretic and antispasmodic effect.