Antitussive, Expectorant and Antiasthmatic Actions of Zhisou Lixiao Capsule
- VernacularTitle:止嗽立效胶囊止咳、祛痰及平喘作用研究
- Author:
Hui WANG
;
Chunlai YOU
;
Mu PEI
;
Yunxing LI
- Publication Type:Journal Article
- Keywords:
Zhisou Lixiao Capsule/pharmacology;
Cough/TCD therapy
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the Antitussive, expectorant and antiasthmatic actions of Zhisou Lixiao capsule(ZLC). Methods: The incubation period and the frequency of cough in mice induced by ammonia water, the secretion of PSP from mouse bronchus and the incubation period of asthma in guinea-pigs induced by histamine were observed. Results: ZLC 0.8~3.2g?kg-1?d-1 ig could obviously prolong the incubative period of cough and decrease the frequency, ZLC 0.8~3.2g?kg-1?d-1 ig could increase the secretion of PSP in mice, 0.5~2.0 g?kg-1?d-1 increase the bronchial secretion in rats, and 1.0~2.0 g?kg-1?d-1 could prolong the incubation period of asthma in guinea-pigs. Conclusion: ZLC exerts a good Antitussive, expectorant and antiasthmatic effect.