Heterogeneous living donor hepatic fat distribution on MRI chemical shift imaging.
10.4174/astr.2015.89.1.37
- Author:
Youngrok CHOI
1
;
Jeong Min LEE
;
Nam Joon YI
;
Hyeyoung KIM
;
Min Su PARK
;
Geun HONG
;
Tae YOO
;
Suk Won SUH
;
Hae Won LEE
;
Kwang Woong LEE
;
Kyung Suk SUH
Author Information
1. Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.
- Publication Type:Original Article
- Keywords:
Fatty liver;
Liver transplantation;
Magnetic resonance imaging;
Transplant donor site
- MeSH:
Fatty Liver;
Humans;
Liver;
Liver Transplantation;
Living Donors*;
Magnetic Resonance Imaging*;
Population Characteristics;
Tissue Donors;
Transplant Donor Site
- From:Annals of Surgical Treatment and Research
2015;89(1):37-42
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: We evaluated the heterogeneity of steatosis in living donor livers to determine its regional differences. METHODS: Between June 2011 and February 2012, 81 liver donors were selected. Fat fraction was estimated using magnetic resonance triple-echo chemical shifting gradient imaging in 13 different regions: segment 1 (S1), S2, S3, and each peripheral and deep region of S4, S5, S6, S7, and S8. RESULTS: There were differences (range, 3.2%-5.3%) in fat fractions between each peripheral and deep region of S4, S6, S7, and S8 (P < 0.001, P = 0.004, P < 0.001, and P = 0.006). Fat deposit amount in S1, S2, S3 and deep regions of S4-S8 were significantly different from one another (F [4.003, 58.032] = 8.684, P < 0.001), while there were no differences among the peripheral regions of S4-S8 (F [2.9, 5.3] = 1.3, P = 0.272) by repeated measure analysis of variance method. And regional differences of the amount of fat deposit in the whole liver increased as a peripheral fat fraction of S5 increased (R2 = 0.428, P < 0.001). CONCLUSION: Multifocal fat measurements for the whole liver are needed because a small regional evaluation might not represent the remaining liver completely, especially in patients with severe hepatic steatosis.
