Effect of Compound Zigui Capsule on ovariotomy rats
- VernacularTitle:复方紫归胶囊对去势大鼠的影响
- Author:
Li ZHANG
- Publication Type:Journal Article
- Keywords:
Compound Ziqui Capsule(CZC);
ovariotomy;
OVX rats;
estrogen;
osteopenia;
bone metabolism
- From:
Chinese Traditional Patent Medicine
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the protection for Compound Zigui Capsule on climacteric syndrome and the mechanism of the action, connected clinical application.Methods: Ovaritectomized rats were used as model of climacteric syndrome and to observed the effects of Compound Zigui Capsule on weight and the index of the organ of OVX rats. Bone metabolism of OVX rats was examined by single photon radionulide emission computed tomograpy.Results: Compound Zigui Capsule could antagonize an increase in body weight and atrophy of the uterus of OVX rats. The estrogenic content and phosphoric level in serum increased significantly. Results of bone metaboism examination showed that the radioactive cound/weight(c/w t) increased. Conclusion: Compound Zigui Capsule had markedly effect on improvement of endocrine disorder, increase of weight, atrophy of the sexual organs and osteopenia in OVX rats.
