Serum lactic dehydrogenase and ?-hydroxybutyric acid in atrophic gastritis type A
- VernacularTitle:A型萎缩性胃炎血清乳酸脱氢酶及?-羟丁酸的研究
- Author:
Yulan LIU
;
Wenbin XIAO
;
Guoyan ZHANG
- Publication Type:Journal Article
- Keywords:
Atrophic gastritis type A;
Lactic dehydrogenase;
? Hydroxybutyric acid
- From:
Chinese Journal of Digestion
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes of lactic dehydrogenase (LDH) and ? hydroxybutyric acid (HBD) in atrophic gastritis type A(AAG) patients. Methods Auto biochemistry instrument was used to detect serum LDH and HBD. Hemoglobin, vitamin B 12 and gastrin were also examined routinely. Results All AAG patients had elevated levels of LDH and HBD in serum and 60 percent of patients had a rise of indirect bilirubin. In the first day after supplement with folic acid and vitamin B 12 , LDH and HBD decreased simultaneously by 30% along with a decrease of indirect bilirubin. The changes of LDH and HBD were earlier than changes of reticulocytes. Conclusions Serum LDH and HBD rise significantly in AAG patients. This might be associated with in situ hemolysis of bone marrow. And it may be a good index for differential diagnosis between AAG and atrophic gastritis type B.
