An experimental study on treating hyperlipidemic fatty liver with simvastatin
- VernacularTitle:辛伐他汀对高脂血症性脂肪肝治疗的实验研究
- Author:
Ming YAN
;
Ruijuan LU
;
Xiaoqing JIA
- Publication Type:Journal Article
- Keywords:
Hyperlipidemia;
Fatty liver;
Simvastatin
- From:
Chinese Journal of Digestion
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of simvastatin in the treatment of hyperlipidemia fatty liver. Methods Animal models were set up by feeding high caloric diet. Liver index (liver weight/body weight), liver function, blood lipid, liver lipid, the content of MDA in serum and liver were assayed before and after therapy with simvastatin. Results Liver index, blood lipid, liver lipid, and the content of MDA in liver as well as in serum increased significantly ( P