Effect of Combination of Rhizoma Coptidis and Fructus Evodiae in Various Proportions on Rat Models with Heat Syndrome Induced by Radix Codonopsis Pilosulae and Radix Astragali seu Hedysari
- VernacularTitle:黄连与吴茱萸不同比例组成的方剂的不同药理作用研究
- Author:
Shengqing LI
;
Zhaosheng HUANG
;
Yaoquan HUANG
;
Pingqing WEI
- Publication Type:Journal Article
- Keywords:
ZUOJIN PILL/phannacology;
GANLU POWDER/pharmacology;
ZHUYU PILL/pharmacology;
HEAT SYNDROME;
DISEASE MODELS,ANIMAL
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To observe the effect of combination of Rhizoma Coptidis (RC) and Fructus Evodiae (FE) in various proportions on rat models with heat syndrome. [Methods] Rat models with heat syndrome were set up by gastric infusion of Radix Codonopsis Pilosulae and Radix Astragali seu Hedysari. Fifty rats were allocated to five groups: normal control group (Group A), model group (Group B), model rats treated with RC and FE at the proportion of 6∶1 (Group C), model rats treated with RC and FE at the proportion of 2∶1 (Group D) and model rats treated with RC and FE at the proportion of 1∶1 (Group E). [Results] Ultrastructure of hepatic cells were improved in Group C, Group D and Group E. Indexes of heat syndrome such as temperature, serum corticosteroid (Cor) level and 17 - hydroxycorticosteroid (17-OHCS) content in homogenate of adrenal glands were decreased in Group C and Group D but stayed unchanged in Group E as compared with Group B ( P
