THE EXPRESSION OF 17? HSD TYPE Ⅰ AND Ⅲ IN IMMATURE MOUSE ADRENAL GLAND
- VernacularTitle:原位RTPCR测定雄性幼鼠肾上腺中Ⅰ、Ⅲ型17?羟甾脱氢酶的表达
- Author:
Hui ZHU
;
Min LIN
;
Zuomin ZHOU
;
Jiahao SHA
- Publication Type:Journal Article
- Keywords:
Adrenal gland;
17? HSD;
in situ RT\|PCR;
Immature mouse
- From:
Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the function of the X\|zone cells in the 5 days old male mouse adrenal gland and the relationship between the function and the sexual differentiation. Methods The technique of in situ RP\|PCR was used to detect the expression of type Ⅰ and Ⅲ 17? HSD mRNA. Results In the cells of X\|zone which located in the interface between adrenal crotex and medulla, there were expressions of type Ⅰ and Ⅲ 17? HSD.Conclusion\ The X\|zone cells of adrenal gland in immature mouse could synthesize androgen, enhanced the male sexual differentiation together with the androgen synthesized from the testis.\;[
