Effect of Plastrum Testudinis on Neural Stem Cell After Focal Cerebral Ischemia
- VernacularTitle:龟板对局灶性脑缺血后神经干细胞的作用
- Author:
Dongfeng CHEN
;
Shaohui DU
;
Yiwei LI
;
Jin ZHANG
;
Hu LI
- Publication Type:Journal Article
- Keywords:
CARAPAX ET PLASTRUM TESTUDINIS/pharmacology;
CEREBRAL ISCHEMIA/TCD therapy;
NEURAL STEM CELLS/drug effects
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Plastrum Testudinis on neural stem cell after focal cerebral ischemia.Methods Rat models of focal cerebral ischemia were established by inserting nylon thread into the anterior cerebral artery.Immunohistochemical method was used to detect the expression of the neuroepithelial stem cell protein(Nestin),neurologic deficit and histological features were also observed.Results Plastrum Testudinis can decrease the neurologic dificit score and promote the expression of Nestin.Conclusion Plastrum Testudinis can alleviate the neurological symptoms and promote the proliferation of neural stem cell after focal cerebral ischemia.
