Mechanism of Borneolum Combined with Rhizoma Chuanxiong in Counteracting Cerebral Ischemia with Reperfusion Injury
- VernacularTitle:冰片与川芎配伍抗脑缺血再灌注损伤作用机理的研究
- Author:
Ping HUANG
;
Qinghe WU
;
Xianglu RONG
;
Jian HAN
- Publication Type:Journal Article
- Keywords:
BORNEOLUM SYNTHETICUM/pharmacology;
LIGUSTICUM CHUANXIONG/pharmacology;
CEREBRAL ISCHEMIA/TCD therapy;
NITRIC OXIDE/analysis;
FREE RADICALS/analysis
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the mechanism of Borneolum combined with Rhizoma Chuanxiong in counteracting cerebral ischemia with reperfusion injury.Methods Rat Model of cerebral ischemia with reperfusion injury was set up by occlusion of bilateral carotid arteries.The effect of Borneolum combined with Rhizoma Chuanxiong on the content of nitric oxide(NO)and free radicals of model rat brain tissue was observed.Results Borneolum combined with Rhizoma Chuanxiong decreased the lipid peroxide(LPO)content and increased the activity of superoxidase(SOD)in model rat brain tissue(P
