Effect of Shema Zhichuan Liquid on Cyclic Nucleotide in Lung Tissue of Rat Models with Asthma
- VernacularTitle:射麻止喘液对哮喘模型大鼠环核苷酸变化的影响
- Author:
Xiaohong LIU
;
Huili LIAO
;
Zhiying LIANG
;
Zhixi CHEN
;
Mingl ZHOU
- Publication Type:Journal Article
- Keywords:
SHEMA ZHICHUAN LIQUID/pharmacology;
SHEGAN MAHUANG DECOCTION/therapeutic use;
ASTHMA/TCD therapy;
ADENOSINE CYCLIC MONOPHOSPHATE;
GUANOSINE CYCLIC MONOPHOSPHATE
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the mechanism of Shema Zhichuan Liquid (SZL) for asthma. Methods Forty rats were allocated to normal control group (Group A), model group (Group B),western medicine group (Group C) and SZL group (Group D). Radioimmunoassay was used to observe the levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) and the ratio of cAMP/cGMP.Results After treatment, cAMP level and cAMP/cGMP ratio were increased and cGMP level decereased in Group C and Group D as compared with Group B (P