Determinination of Taurine in Taurine Soft Capsules by Pre-column Derivatization HPLC
- VernacularTitle:柱前衍生化HPLC法测定牛磺酸软胶囊中牛磺酸的含量
- Author:
Yunlan LI
- Publication Type:Journal Article
- Keywords:
RP HPLC;
Taurine Soft Capsules;
taurine;
pre column derivatization
- From:
Chinese Traditional Patent Medicine
1992;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To develop a method for the determination of taurine in Taurine Soft Capsules by RP HPLC.Methods: Taurine was derivated by phthalaldehyde and ethanethiol. The analytical column was C 18 . The UV detective wavelength was set at 360nm. The mobile phase was methanol water phosphate buffer (1∶1∶1). The external standard method was used. Results: The recovery was 95.8%～107.2%. RSD was 2.1%. The linear range of concentration was 6.7 ～40.4 mg/mL. The minimum detectability was 2.47mg/mL. Conclusions: The method is simple, quick and accurate.
