Protective effect of Yunnan folk medicine Rhodobryum roseum on experimental myocardial ischemia of rat
- VernacularTitle:民族药滇产回心草对大鼠实验性心肌缺血的保护作用
- Author:
Xiuling LEI
;
Rongping ZHANG
;
Xuefeng DONG
;
Qi PAN
;
Qixin YAN
;
Tianhao LUO
;
Guangxi HE
- Publication Type:Journal Article
- Keywords:
Rhodobryum roseum (Hedw) Limpr.;
experimental myocardial ischemia;
lactic dehydrogenase (LDH);
creatine phosphokinase (CPK);
superoxide dismutase (SOD);
malondialdehyde (MDA)
- From:
Chinese Traditional and Herbal Drugs
1994;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To study the protective effect of Rodobryum roseum (Hedw) Limpr. on acute myocardial ischemia. Methods Rat acute myocardial ischemia models were prepared by ligating their left coronary arteries. Changes of their S-T segment was observed on lead Ⅱ dynamic ECG. Degree of ischemia was assessed by the extent of S-T segment elevation. Lactic dehydrogenase (LDH), creative phosphokinase (CPK), superoxide dismutase (SOD) and malondialdehyde (MDA) were determined at the same time. Results R. roseum can significantly alleviate S-T segment elevation, being most evident at the dose of 2 g/kg (P
