Study on the correlation of the cytokine secreted by the endometrium focus and the microenvirment of the fleument fluid
- VernacularTitle:子宫内膜异位症病灶分泌的细胞因子与腹腔液微环境关系的研究
- Author:
Ying GAO
;
Yi LIU
;
Lilan LUO
- Publication Type:Journal Article
- Keywords:
Endometriosis;
Cytokines;
Microcirculation
- From:
Chinese Journal of Obstetrics and Gynecology
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of endometriotic focus and peritoneal fluid as well as its effect on reproduction Methods Forty three women with surgical treatment or laproscope with infertility are divided into endometriosis group (24 cases) and normal pelvic group (control group 19 cases) The pathophysiology of patient′s peritoneal fluid, celiac macrophages and endometriotic cells are analyzed by chemotactic test on monocytes, dot blot hybridize, enzyme linked immunoadsorbent assay and the level of cytoplasmic [Ca 2+ ]i respectively Meanwhile, the influence of peritoneal fluid and endometriotic cells to sperm motivity as well as the effects to rat embryo cleavage are evaluated Results The monocyte moving distance induced by peritoneal fluid in endometriosis group Vs control is (87 2?9 4) ?m Vs (51 9?3 7) ?m ( P